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Invitrogen™ ACTA1 Recombinant Rabbit Monoclonal Antibody (K01_2N43)
Description
ACTA1 Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Western Blot
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Specifications
Specifications
| Antigen | ACTA1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | K01_2N43 |
| Concentration | 0.20 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | ACTA1 |
| Gene Accession No. | P68133, P68136 |
| Gene Alias | AA959943; ACTA; Acta1; Acta-2; actin alpha 1; actin alpha 1, skeletal muscle; actin, alpha 1, skeletal muscle; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; Acts; Actsk-1; alpha actin 1; alpha-actin-1; ASMA; beta actin; CFTD; CFTD1; CFTDM; cytoplasmic beta-actin; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; skeletal alpha actin; unnamed protein product |
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