Invitrogen™ ACSL5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589639

Product Code. 16527471

Description

Immunogen sequence: GQTECTGGCT FTLPGDWTSG HVGVPLACNY VKLEDVADMN YFTVNNEGEV CIKGTNVFKG YLKDPEKTQE ALDSDGWLHT GDIGRWLPNG TLKIIDRKKN IFKLAQGEYI APEKIENIYN RSQPVLQIFV HGESLRSSLV GVVVPDTDVL PSFAAKLGVK GSFEELCQNQ VVREAILEDL QKIGKESGLK TFEQVKAIFL HPEPFSIENG LLTPTLKAKR GELSKYFRTQ IDSLYEHIQD; Positive Samples: HL-60, Mouse liver, Rat liver; Cellular Location: Endoplasmic reticulum, Endoplasmic reticulum membrane, Mitochondrion, Mitochondrion outer membrane, Single-pass type III membrane protein.

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ACSL5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACSL5
• Gene Alias: 1700030F05Rik; ACS2; ACS5; Acsl5; acyl-CoA synthetase 5; acyl-CoA synthetase long chain family member 5; acyl-CoA synthetase long-chain family member 5; Arachidonate--CoA ligase; FACL5; FACL5 for fatty acid coenzyme A ligase 5; fatty acid coenzyme A ligase 5; fatty acid Coenzyme A ligase, long chain 5; fatty-acid-Coenzyme A ligase, long-chain 5; HGNC:16526; LACS 5; Long-chain acyl-CoA synthetase 5; long-chain fatty acid coenzyme A ligase 5; long-chain-fatty-acid--CoA ligase 5; UNQ633/PRO1250; zgc:92083
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 433256, 51703, 94340
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.74 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O88813, Q8JZR0, Q9ULC5
• Gene Symbols: ACSL5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 500-739 of human ACSL5 (NP_0573182).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG