Invitrogen™ ACOT8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588959

Product Code. 16567021

Description

Immunogen sequence: MSSPQAPEDG QGCGDRGDPP GDLRSVLVTT VLNLEPLDED LFRGRHYWVP AKRLFGGQIV GQALVAAAKS VSEDVHVHSL HCYFVRAGDP KLPVLYQVER TRTGSSFSVR SVKAVQHGKP IFICQASFQQ AQPSPMQHQF SMPTVPPPEE LLDCETLIDQ YLRDPNLQKR YPLALNRIAA QEVPIEIKPV NPSPLSQLQR MEPKQMFWVR ARGYIGEGDM; Positive Samples: Jurkat, Raji, U-87MG, HeLa; Cellular Location: Peroxisome.

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It may mediate Nef-induced down-regulation of CD4. It may be involved in the metabolic regulation of peroxisome proliferation.

Specifications

• Antigen: ACOT8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACOT8
• Gene Alias: 4,8-dimethylnonanoyl-CoA thioesterase; 48-dimethylnonanoyl-CoA thioesterase; ACOT8; ACTEIII; Acyl-CoA thioesterase 8; acyl-coenzyme A thioesterase 8; choloyl-CoA hydrolase; choloyl-coenzyme A thioesterase; hACTE-III; HIV-Nef associated acyl-CoA thioesterase; HIV-Nef-associated acyl-CoA thioesterase; HNAACTE; hTE; long-chain fatty-acyl-CoA hydrolase; NAP1; Nef (lentivirus myristoylated factor) associated protein 1; palmitoyl-CoA hydrolase; peroxisomal acyl-CoA thioesterase 1; peroxisomal acyl-CoA thioesterase 2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; peroxisomal long-chain acyl-CoA thioesterase 1; PTE1; PTE-1; PTE2; PTE-2; Thioesterase II; thioesterase III
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10005
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.67 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O14734
• Gene Symbols: ACOT8
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACOT8 (NP_0054602).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG