Invitrogen™ Aconitase 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529037

Product Code. 13463157

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain, rat brain. Predicted reactivity: Mouse (96%), Rat (96%), Xenopus laevis (86%), Pig (96%), Chicken (92%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Specifications

• Antigen: Aconitase 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Aco2
• Gene Alias: Aco2; Aco-2; Aco3; Aconitase; aconitase 2; aconitase 2, mitochondrial; aconitase precursor; aconitate hydratase, mitochondrial; ACONM; citrate hydro-lyase; D10Wsu183e; epididymis secretory sperm binding protein Li 284; heart aconitase; heart aconitase precursor; HEL-S-284; hypothetical protein; ICRD; MGC20605; MGC33908; mitochondrial aconitase; mitochondrial aconitase (nuclear aco2 gene); OCA8; OPA9; RP3-347H13.8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11429, 50, 79250
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.82 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q99798, Q99KI0, Q9ER34
• Gene Symbols: Aco2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Aconitase 2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG