Invitrogen™ ACMSD Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5113272

Product Code. 17131134

Description

ACMSD Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].

Specifications

• Antigen: ACMSD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACMSD
• Gene Alias: 2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Acmsd; amino carboxymuconate semialdehyde decarboxylase; aminocarboxymuconate semialdehyde decarboxylase; Picolinate carboxylase; zgc:162888
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 130013, 171385
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 4 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q8R5M5, Q8TDX5
• Gene Symbols: ACMSD
• Immunogen: Recombinant Human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase protein (33-129AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG