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Invitrogen™ Acinus Polyclonal Antibody

Product Code. 12858152
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12858152 100 μg 100µg
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Product Code. 12858152 Supplier Invitrogen™ Supplier No. PA519938

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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~220kDa. A suggested positive control is K562 cell lysate. PA5-19938 can be used with blocking peptide PEP-0063.

ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Acinus
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ACIN1
Gene Accession No. Q9UKV3
Gene Alias 2610036I19Rik; 2610510L13Rik; Acin1; ACINUS; acinusL; acinusS; Acn; apoptotic chromatin condensation inducer 1; apoptotic chromatin condensation inducer in the nucleus; C79325; DKFZp667N107; fSAP152; functional spliceosome-associated protein 152; KIAA0670; mKIAA0670
Gene Symbols ACIN1
Host Species Rabbit
Immunogen A peptide corresponding to amino acids near the C-terminus of the cleaved active peptide p17.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22985
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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