Acetylcholine chloride, 98+%

Product Code. 11331537

Brand: Thermo Scientific Alfa Aesar L02168.22

Description

CAS: 60-31-1 | C7H16ClNO2 | 181.66 g/mol

Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Acetylcholine chloride acts as an endogenous neurotransmitter at cholinergic synapses. The compound has been shown to have ophthalmological uses and can be broken down quickly by choliesterases. Acetylcholine influences many basic cells functions, such as mitosis, cells differentiation, cytoskeletal organization, and cell to cell contact, among other functions. It reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis.The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Solubility
Soluble in water (600 g/L at 20°C), alcohol, DMSO (36 mg/ml at 25°C), and ethanol (36 mg/ml at 25°C). Insoluble in ether.

Notes
Store away from moisture. Store under dry inert gas. Incompatible with heat,oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 60-31-1
• Molecular Formula: C7H16ClNO2
• Molecular Weight (g/mol): 181.66
• MDL Number: MFCD00011698
• InChI Key: JUGOREOARAHOCO-UHFFFAOYSA-M
• Synonym: acetylcholine chloride, miochol, acecoline, chloroacetylcholine, arterocoline, acecholin, ovisot, ach chloride, azetylcholinchlorid, 2-acetyloxy-n,n,n-trimethylethanaminium chloride
• PubChem CID: 6060
• ChEBI: CHEBI:2417
• IUPAC Name: 2-acetyloxyethyl(trimethyl)azanium;chloride
• SMILES: CC(=O)OCC[N+](C)(C)C.[Cl-]

• Melting Point: 149°C to 152°C
• Quantity: 100 g
• Beilstein: 3571875
• Sensitivity: Very Hygroscopic
• Merck Index: 14,87
• Solubility Information: Soluble in water (600g/L at 20°C),alcohol,DMSO (36mg/ml at 25°C),and ethanol (36mg/ml at 25°C). Insoluble in ether.
• Formula Weight: 181.66
• Percent Purity: ≥98%
• Chemical Name or Material: Acetylcholine chloride

Seguridad y manipulación

Nombre del producto

• Acetylcholine chloride

Palabra de advertencia

• Warning

Clasificación

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Indicaciones de peligro

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Consejos de prudencia

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Otros peligros

• MIXTURE LIST-Contains : Acetylcholine chloride

SDS

RUO – Research Use Only