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  5. Tocris Bioscience™ AC 5216

Tocris Bioscience™ AC 5216
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Product Code. 18756218
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18756218

Brand: Tocris Bioscience™ 5281/10

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Description

Selective TSPO ligand

AC 5216 is a ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type AC 5216
Purity >98%
Molecular Weight (g/mol) 401.46
Inhibitors AC 5216

For Research Use Only

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