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  5. Tocris Bioscience™ ABT 594 Hydrochloride

Tocris Bioscience™ ABT 594 Hydrochloride
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Product Code. 18759316
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Product Code. 18759316 Supplier Tocris Bioscience™ Supplier No. 6576/10

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Description

Selective α4β2 nAChR agonist

ABT 594 hydrochloride is a selective α4β2 nAChR agonist (EC50 = 140 nM for human α4β2 nAChRs, in vitro). Exhibits >900-fold selectivity for α4β2 nAChRs over other neurotransmitter receptors. Displays analgesic properties in various animal models of pain. Potentiates gabapentin mediated analgesia. Also demonstrates cognitive enhancement effects in rodent model of attention deficit.
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Specifications

Chemical Name or Material (R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride
CAS 203564-54-9
Synonym Tebanicline
Quantity 10 mg
Molecular Formula C9H11ClN2O.HCL
Formula Weight 235.11
Purity 98%
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