missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Sulfanilides
  8. Abrocitinib, MedChemExpress

Abrocitinib, MedChemExpress

Product Code. 16496827
Encompass_Preferred
Change view
Click to view available options
Quantity:
5 mg
10 mg
Unit Size:
10mg
5mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16496827 5 mg 5mg
16484128 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 16496827 Supplier Medchem Express Supplier No. HY107429
 Restricted Item
Estimated Shipment: 10-08-2026
Add to basket
Add to basket
This item is not returnable. View return policy

Description

MedChemExpress Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 (IC50, 1.253 μM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease.

Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 (IC50, 1.253 μM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease.

Specifications

Chemical Name or Material Abrocitinib
CAS 1622902-68-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C14H21N5O2S
Quantity 5 mg
Synonym PF-04965842
Solubility Information DMSO : 125 mg/mL (386.51 mM; Need ultrasonic)
SMILES CN([C@H]1C[C@@H](NS(CCC)(=O)=O)C1)C2=C3C(NC=C3)=NC=N2
Molecular Weight (g/mol) 323.41
Formula Weight 323.41
Percent Purity 99.04%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.