Invitrogen™ ABHD3 Monoclonal Antibody (A5D4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA544987

Product Code. 17868082

Description

ABHD3 Monoclonal Antibody for Western Blot

The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The α/β hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostlyuncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD3 is a 409 amino acid single-pass type II membrane protein. ABHD4 is involved in an alternative synthesis pathway of NAE (N-acyl ethanolamine). Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling.

Specifications

• Antigen: ABHD3
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Plant
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: A5D4
• Conjugate: Unconjugated
• Gene Alias: AA675331; ABHD3; abhydrolase domain containing 3; abhydrolase domain-containing protein 3; alpha/beta hydrolase domain containing protein 3; LABH3; Lung alpha/beta hydrolase 3; mmLABH3; Phospholipase ABHD3
• Immunogen: Recombinant full length protein within Camellia.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid