Invitrogen™ ABCG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595071

Product Code. 16314345

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: U87 whole cell, SMMC whole cell, HELA whole cell, COLO320 whole cell, MCF-7 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1.

Specifications

• Antigen: ABCG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCG1
• Gene Alias: ABC transporter 8; ABC8; ABCG1; ATP binding cassette subfamily G member 1; ATP-binding cassette 8; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette, subfamily G (WHITE), member 1; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette, subfamily G, member 1; AW413978; homolog of Drosophila white; I79_011524; MGC34313; White; White protein homolog; white protein homolog (ATP-binding cassette transporter 8); WHITE1; WHT1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11307, 85264, 9619
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P45844, Q64343
• Gene Symbols: ABCG1
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ABCG1 (627-647aa ETCHFQKSEAILRELDVENAK).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG