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Invitrogen™ ABCE1 Polyclonal Antibody
Description
Suggested positive control: antigen standard for ABCE1 (transient overexpression lysate), 293 whole cell lysate, Hela whole cell lysate, HeLa and 293 cell lysates.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Specifications
Specifications
| Antigen | ABCE1 |
| Applications | Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% sodium azide |
| Gene | ABCE1 |
| Gene Accession No. | P61221 |
| Gene Alias | 2'-5'-oligoadenylate-binding protein; ABC 38; ABC38; ABCE 1; ABCE1; ATP binding cassette subfamily E member 1; ATP-binding cassette sub-family E member 1; ATP-binding cassette, subfamily E (OABP), member 1; ATP-binding cassette, sub-family E (OABP), member 1; ATP-binding cassette, subfamily E, member 1; C79080; HP68; HuHP68; OABP; OK/SW-cl.40; Ribonuclease 4 inhibitor; ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; RLI; RLI1; RNase 4 inhibitor; RNase L inhibitor; RNase L inhibitor 1; RNASEL1; Rnaseli; RNS41; RNS4I; RNS4l (Eye) |
| Gene Symbols | ABCE1 |
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