Invitrogen™ ABCB8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5120826

Product Code. 17742224

Description

Positive test controls include: MCF7, Jurkat, HepG2, HeLa, Mouse heart, Mouse skin, Mouse kidney, Rat heart. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein. Immunogen sequence: GFEVLKDFTL TLPPGKIVAL VGQSGGGKTT VASLLERFYD PTAGVVMLDG RDLRTLDPSW LRGQVVGFIS QEPVLFGTTI MENIRFGKLE ASDEEVYTAA REANAHEFIT SFPEGYNTVV GERGTTLSGG QKQRLAIARA LIKQPTVLIL DEATSALDAE SERVVQEALD RASAGRTVLV IAHRLSTVRG AHCIVVMADG RVWEAGTHEE LLKKGGLYAE LIRRQALDAP RTAAPPPKKP EGPRSHQHKS.

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: ABCB8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCB8
• Gene Alias: 4833412N02Rik; AA409895; ABC transporter 8; Abcb8; ATP binding cassette subfamily B member 8; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8; ATP-binding cassette, sub-family B (MDR/TAP), member 8; ATP-binding cassette, sub-family B, member 8; EST328128; hypothetical protein LOC548340; MABC1; M-ABC1; mitochondrial ABC protein; mitochondrial ATP-binding cassette 1; mitochondrial potassium channel ATP-binding subunit; mitochondrial sulfonylurea-receptor; MITOSUR; zgc:113037
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11194, 362302, 74610
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q5RKI8, Q9CXJ4, Q9NUT2
• Gene Symbols: ABCB8
• Immunogen: Recombinant Protein (or fragment).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG