missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Fluorobenzenes
  8. ABBV-744, MedChemExpress

ABBV-744, MedChemExpress

Product Code. 16467277
Encompass_Preferred
Click to view available options
Quantity:
5 mg
10 mg
25 mg
50 mg
Unit Size:
10mg
25mg
50mg
5mg
This item is not returnable. View return policy

Product Code. 16467277

Brand: Medchem Express HY112090

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with drug-like properties enable the investigation of its antitumor efficacy and tolerability.

ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with drug-like properties enable the investigation of its antitumor efficacy and tolerability.

Specifications

Chemical Name or Material ABBV-744
CAS 2138861-99-9
Color White
Purity Grade Notes Research
Molecular Formula C28H30FN3O4
Quantity 5 mg
Solubility Information DMSO : 100 mg/mL (203.44 mM; Need ultrasonic)
SMILES CC(O)(C)C1=CC(C(C2=C3NC(C(NCC)=O)=C2)=CN(C)C3=O)=C(OC4=C(C)C=C(F)C=C4C)C=C1
Molecular Weight (g/mol) 491.55
Formula Weight 491.55
Percent Purity 98.22%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.