Invitrogen™ AADAT Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA532646

Product Code. 13444319

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Monkey (88%); Dog, Elephant (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.

Specifications

• Antigen: AADAT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Aadat
• Gene Alias: 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; AadAT; Aadt; AI875679; alpha-aminoadipate aminotransferase; aminoadipate aminotransferase; KAT/AadAT; Kat2; KATII; KYAT2; kynurenine aminotransferase 2; kynurenine aminotransferase II; kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; kynurenine--oxoglutarate; Kynurenine--oxoglutarate aminotransferase II; kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; L kynurenine/alpha aminoadipate aminotransferase; mKat-2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51166
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q8N5Z0
• Gene Symbols: Aadat
• Immunogen: Synthetic 17 amino acid peptide from internal region of human AADAT.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG