Invitrogen™ A2BP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5103622

Product Code. 16630075

Description

Antibody detects endogenous levels of total FOX1.

Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

Specifications

• Antigen: A2BP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rbfox1
• Gene Alias: 2BP1; A FOX-1; A2BP; A2BP1; ataxin 2 binding protein 1; ataxin 2-binding protein 1; ataxin-2-binding protein 1; FOX1; fox-1; fox-1 homolog A; fox-1-like RNA-binding protein 1; hexaribonucleotide binding protein 1; hexaribonucleotide binding protein 1 isoform alpha; hexaribonucleotide binding protein 1 isoform beta; hexaribonucleotide-binding protein 1; HRNBP1; MNCb-3035; RBFOX1; RNA binding fox-1 homolog 1; RNA binding protein fox-1 homolog 1; RNA binding protein, fox-1 homolog (C. elegans) 1; RNA binding protein, fox-1 homolog 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 268859, 302920, 54715
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9JJ43, Q9NWB1
• Gene Symbols: Rbfox1
• Immunogen: A synthesized peptide derived from human RBFOX1(Accession Q9NWB1), corresponding to amino acid residues A22-H72.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG