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Invitrogen™ A20A3 Polyclonal Antibody
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Product Code. 17177538 Shop All Thermo Scientific Products
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400 μL
Unit Size:
400µL
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17177538 400 μL 400µL
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Product Code. 17177538 Supplier Invitrogen™ Supplier No. PA5116305

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Description

Rabbit Polyclonal Antibody

A20A3 Polyclonal Antibody for Western Blot

Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
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Specifications

Antigen A20A3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene ANKRD20A3
Gene Accession No. Q5VUR7
Gene Alias ANKRD20A3; ankyrin repeat domain 20 family member A3; ankyrin repeat domain 20 family, member A3; ankyrin repeat domain 20A-related; ankyrin repeat domain-containing protein 20A3
Gene Symbols ANKRD20A3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 794-821 amino acids from the C-terminal region of human ANKRD20A3.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 441425
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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