Invitrogen™ A1BG Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588154

Product Code. 16516471

Description

Immunogen sequence: LSGVDFQLRR GEKELLVPRS STSPDRIFFH LNAVALGDGG HYTCRYRLHD NQNGWSGDSA PVELILSDET LPAPEFSPEP ESGRALRLRC LAPLEGARFA LVREDRGGRR VHRFQSPAGT EALFELHNIS VADSANYSCV YVDLKPPFGG SAPSERLELH VDGPPPRPQL RATWSGAVLA GRDAVLRCEG PIPDVTFELL REGETKAVKT VRTPGAAANL ELIFVGPQHA GNYRCRYRSW VPHTFESELS DPVELLVAES; Positive Samples: SKOV3, HeLa, Mouse kidney, Rat liver.

Alpha-1-B glycoprotein (A1BG) which is a plasma protein with no known function belongs to the immunoglobulin superfamily. Although the human A1BG has been known for four decades, and the information about the amino acid sequence, chromosomal assignment, and even genetic polymorphism in different populations have been known, no biological function has been suggested. A1BG (Mr approximately equal to 63,000) consists of one polypeptide chain of 474 amino acids with four glucosamine oligosaccharides. The polypeptide has five intrachain disulfide bonds and consists of five repeating structural domains, each containing about 95 amino acids and one disulfide bond. Recently human cysteine-rich secretory protein 3 (CRISP-3) has been found to be a binding partner of A1B, suggesting the A1BG-CRISP-3 complex displays a protecting function from a potentially harmful effect of free CRISP-3 in circulation.

Specifications

• Antigen: A1BG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: A1BG
• Gene Alias: A1B; A1bg; A1bg {ECO:0000312; ABG; Alpha-1-B glycoprotein; alpha-1-B-glycoprotein; alpha-1B-glycoprotein; alpha1B-glycoprotein; C44; DKFZp686F0970; epididymis secretory sperm binding protein Li 163pA; GAB; HEL-S-163pA; HYST2477; Liver regeneration-related protein 1; RGD:69417}
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 11.07 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P04217
• Gene Symbols: A1BG
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 236-495 of human A1BG (NP_5706022).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG