A1874, MedChemExpress

Product Code. 16474808

Brand: Medchem Express HY11430510mg

Description

MedChemExpress A1874 is a nutlin-based (MDM2 ligand) and BRD4-degrading PROTAC with a DC50 of 32 nM (induce BRD4 degradation in cells). Effective in inhibiting many cancer cell lines proliferation.

A1874 is a nutlin-based (MDM2 ligand) and BRD4-degrading PROTAC with a DC50 of 32 nM (induce BRD4 degradation in cells). Effective in inhibiting many cancer cell lines proliferation.

Specifications

• Chemical Name or Material: A1874
• CAS: 2064292-12-0
• Color: Light Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₅₈H₆₂Cl₃F₂N₉O₇S
• Quantity: 10 mg
• Solubility Information: DMSO : 150 mg/mL (127.81 mM; Need ultrasonic)
• SMILES: ClC(C=C1)=CC=C1C2=N[C@H](C3=NN=C(C)N3C4=C2C(C)=C(C)S4)CC(NCCOCCOCCOCCNC(C5=CC(OC)=C(NC([C@H]6[C@H](C7=C(F)C(Cl)=CC=C7)[C@](C8=CC=C(Cl)C=C8F)(C#N)[C@H](CC(C)(C)C)N6)=O)C=C5)=O)=O
• Molecular Weight (g/mol): 1173.59
• Formula Weight: 1173.59
• Percent Purity: 99.28%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only