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Tocris Bioscience™ A01
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Product Code. 18732459
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18732459 10 mg 10mg
18767078 50 mg 50mg
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Product Code. 18732459 Supplier Tocris Bioscience™ Supplier No. 5397/10

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Description

High affinity Smurf1 inhibitor; enhances BMP signaling

A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM). Attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.
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Specifications

Purity >98%
Quantity 10 mg
Product Type A01
Molecular Weight (g/mol) 512.93
Inhibitors A01

For Research Use Only

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