missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Phenoxy compounds
  8. A 839977, MedChemExpress

A 839977, MedChemExpress

Product Code. p-200096876
Encompass_Preferred
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 16495928

Brand: Medchem Express HY13954

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress A 839977 is a P2X7 selective antagonist; it blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20 nM, 42 nM and 150 nM respectively) and reduces inflammatory and neuropathic pain in animal models; the antihyperalgesic effects of P2X7 receptor blockade are mediated by blocking the release of IL-1beta.

A 839977 is a P2X7 selective antagonist

Specifications

Chemical Name or Material A 839977
CAS 870061-27-1
Color White
Purity Grade Notes Research
Molecular Formula C19H14Cl2N6O
Quantity 10 mg
Solubility Information DMSO : ≥ 100 mg/mL (241.98 mM)
SMILES ClC1=C(Cl)C(N2N=NN=C2NCC3=CC=CC=C3OC4=NC=CC=C4)=CC=C1
Molecular Weight (g/mol) 413.26
Formula Weight 413.26
Percent Purity 98.01%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.