A 839977, MedChemExpress

Product Code. 16495928

Brand: Medchem Express HY13954

Descripción

MedChemExpress A 839977 is a P2X7 selective antagonist; it blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20 nM, 42 nM and 150 nM respectively) and reduces inflammatory and neuropathic pain in animal models; the antihyperalgesic effects of P2X7 receptor blockade are mediated by blocking the release of IL-1beta.

A 839977 is a P2X7 selective antagonist

Especificaciones

• Chemical Name or Material: A 839977
• CAS: 870061-27-1
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₁₉H₁₄Cl₂N₆O
• Quantity: 10 mg
• Solubility Information: DMSO : ≥ 100 mg/mL (241.98 mM)
• SMILES: ClC1=C(Cl)C(N2N=NN=C2NCC3=CC=CC=C3OC4=NC=CC=C4)=CC=C1
• Molecular Weight (g/mol): 413.26
• Formula Weight: 413.26
• Percent Purity: 98.01%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): COVID-19-immunoregulation

Research purposes only