Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade, Thermo Scientific™

Spectinomycin dihydrochloride pentahydrate, CAS # 22189-32-8, is the hydrochloride salt form of spectinomycin, an aminocyclitol compound showing antibacterial and antimicrobial activities.

Brand:  Thermo Scientific Alfa Aesar J61820.06

Product Code. 15470207

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Spectinomycin dihydrochloride pentahydrate is derived from Streptomyces spectabilis and presents antibacterial and antimicrobial activities
• Spectinomycin hydrochloride is a compound that inhibits the 30S ribosomal subunit of bacteria and interrupts protein synthesis and peptide elongation, leading to bacterial cell death

Application

• Spectinomycin dihydrochloride pentahydrate is a compound that is active against gram-negative bacteria
• In the laboratory, this compound is used in cell culture applications
• It prevents contamination and can be used to select for resistant bacteria and plant cells containing the marker gene Spcr
• It has been used to study respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica
• In genetic approaches, this compound can be used to amplify the plasmid copy number

Specifications

• CAS: 22189-32-8
• Quantity: 5g
• MDL Number: MFCD00150886
• Solubility Information: Soluble in water;Soluble in water,methanol,dimethyl sulfoxide,ethanol and dimethyl formamide.
• SMILES: [H+].[H+].O.O.O.O.O.[Cl-].[Cl-].CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O
• Molecular Weight (g/mol): 495.34
• ChEBI: CHEBI:9217
• Grade: Cell Culture

• Color: White
• Molecular Formula: C14H36Cl2N2O12
• Synonym: Spectinomycin dihydrochloride
• InChI Key: DCHJOVNPPSBWHK-UXXUFHFZSA-N
• IUPAC Name: dihydrogen (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.0³,⁸]tetradecan-7-one pentahydrate dichloride
• PubChem CID: 67108398
• Formula Weight: 495.35 (405.28 Anhydrous)
• Chemical Name or Material: Spectinomycin dihydrochloride pentahydrate

Safety and Handling

Product Identifier

• Spectinomycin dihydrochloride pentahydrate

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Spectinomycin dihydrochloride pentahydrate