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  5. Tocris Bioscience™ TAK 960 hydrochloride

Tocris Bioscience™ TAK 960 hydrochloride
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Product Code. 18732418
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18732418

Brand: Tocris Bioscience™ 5403/50

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This item is not returnable. View return policy

Description

Potent and selective PLK1 inhibitor

TAK 960 hydrochloride is a potent PLK1 inhibitor (IC50 values are 0.8, 16.9 and 50.2 nM for PLK1, PLK2 and PLK3 respectively). Exhibits >20-fold selectivity for PLK1 over FAK, MLCK and FES, and has minimal activity against a panel of 282 other kinases. Inhibits proliferation of a range of cancer cell lines in vitro and inhibits tumor growth of multiple human cancer cell xenografts in vivo. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

CAS 2108449-45-0
Quantity 50 mg
Product Type TAK 960 hydrochloride
Purity >98%
Molecular Weight (g/mol) 598.06

For Research Use Only

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