R&D Systems™ Recombinant Human IL-2 R beta Fc Chimera Protein

Product Code. 18769496

Brand: R&D Systems™ 109192B050

Description

Measured by its ability to inhibit Recombinant Human IL-15 (Catalog # 247-ILB ) dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 1.75-14.0 μg/mL.

Specifications

• Accession Number: P14784.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 3560
• Molecular Weight (g/mol): M.W.-observed: 62 - 68 kDa, under reducing conditions., M.W.-theroretical: 51 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human IL-2 R beta protein Human IL-2 R beta (Ala27-Asp239) (C-terminus) Accession # P14784.1 IEGRMD Human IgG1 (Pro100-Lys330) (N-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD122, CD122 antigen, high affinity IL-2 receptor beta subunit, High affinity IL-2 receptor subunit beta, IL-15 R beta, IL-2 receptor subunit beta, IL2R beta, IL-2 R subunit beta, IL2RB, IL-2 RB, interleukin 15 receptor, beta, interleukin 2 receptor, beta, interleukin-2 receptor subunit beta, P70-75, p75
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 250 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: IL-2 R beta