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Tocris Bioscience™ 5-Iodotubercidin
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Product Code. 18054072
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Quantity:
1 mg
Unit Size:
1mg
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Product Code. 18054072

Brand: Tocris Bioscience™ 1745/1

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This item is not returnable. View return policy

Description

Potent adenosine kinase inhibitor; also inhibits nucleoside transporters and a range of other kinases

Potent adenosine kinase inhibitor (IC50 = 26 nM). Also nucleoside transporter inhibitor (IC50 values are < 25 nM, 7 μM and 15 μM for inhibition of [3H]adenosine, [3H]uridine and [3H]formycin B uptake respectively). Strongly stimulates glycogen synthesis in hepatocytes via activation of glycogen synthase. Also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC (IC50 values are 0.4, 3.5, 5-10, 5-10, 10.9 and 27.7 μM respectively). Decreases hippocampal DNA methylation through adenosine kinase inhibition in vivo.
TRUSTED_SUSTAINABILITY

Specifications

CAS 24386-93-4
Quantity 1 mg
Molecular Formula C11H13IN4O4
Formula Weight 392.15
Purity 97%
Molecular Weight (g/mol) 392.15
Chemical Name or Material 5-Iodotubercidin
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