Thermo Scientific Chemicals 5-Fluorouracil, 99%

Product Code.	Quantity	Packaging	unitSize
10348170	1 g	Glass bottle	1g
10697552	5 g	Glass bottle	5g
11906531	25 g	Glass bottle	25g
15159263	100 g	Glass bottle	100g

Product Code. 10348170 Supplier Thermo Scientific Chemicals Supplier No. 228440010

Descripción

5-Fluorouracil, CAS # 51-21-8, is an analogue base composed of uracil with a position 5 hydrogen fluorine substitution. | CAS: 51-21-8 | C4H3FN2O2 | 130.08 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 5-Fluorouracil is an antimetabolite and antineoplastic that prevents DNA synthesis by blocking conversion of deoxyuridylic acid

• 5-Fluorouracil can replace uracil in RNA and prevent protein synthesis and cell growth

Applications

• 5-Fluorouracil can be used for laboratory research on tumor growth and immunosuppression

• 5-Fluorouracil may also be appropriate for laboratory studies of neurotoxicity, cell lysis, and DNA damage

Especificaciones

Identificadores de productos químicos

• CAS: 51-21-8
• Molecular Formula: C4H3FN2O2
• Molecular Weight (g/mol): 130.08
• MDL Number: MFCD00006018
• InChI Key: GHASVSINZRGABV-UHFFFAOYSA-N
• Synonym: 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton
• PubChem CID: 3385
• ChEBI: CHEBI:46345
• IUPAC Name: 5-fluoro-1H-pyrimidine-2,4-dione
• SMILES: FC1=CNC(=O)NC1=O

• Melting Point: 278.0°C to 282.0°C
• Color: White
• Boiling Point: 190.0°C to 200.0°C (0.1 mmHg)
• Loss on Drying: 0.5% (80°C, 4 hrs) (in vacuum) max.
• Infrared Spectrum: Authentic
• Assay Percent Range: 99%
• Packaging: Glass bottle
• Quantity: 1 g
• Beilstein: 24,IV,1229
• Merck Index: 15,4213
• Solubility Information: Solubility in water: 12.2g/L (20°C). Other solubilities: 2.9g/L (20°C) in ethanol,readily soluble in aqueous alkali solutions,soluble in dmso
• Formula Weight: 130.08
• Percent Purity: 99%
• Physical Form: Crystalline Powder
• Chemical Name or Material: 5-Fluorouracil

Seguridad y manipulación

Nombre del producto

• 5-Fluorouracil

Palabra de advertencia

• Danger

Clasificación

• Acute toxicity Category 3
• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Germ cell mutagenicity Category 2
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Indicaciones de peligro

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H341-Suspected of causing genetic defects.
• H361d-Suspected of damaging the unborn child.
• H335-May cause respiratory irritation.
• H312-Harmful in contact with skin.
• H332-Harmful if inhaled.
• H301-Toxic if swallowed.

Consejos de prudencia

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P337+P313-If eye irritation persists: Get medical advice/attention.

RUO – Research Use Only