5-Fluoro-2'-deoxyuridine, 98+%

CAS: 50-91-9 | C9H11FN2O5 | 246.19 g/mol

Brand:  Thermo Scientific Alfa Aesar L16497.ME

Product Code. 11379205

Description

5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Notes
Store in a cool place.Incompatible with strong oxidizing agents and strong bases.

Chemical Identifiers

• CAS: 50-91-9
• Molecular Weight (g/mol): 246.19
• InChI Key: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
• PubChem CID: 5790
• IUPAC Name: 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

• Molecular Formula: C9H11FN2O5
• MDL Number: MFCD00006530
• Synonym: floxuridine, 2'-deoxy-5-fluorouridine, 5-fluoro-2'-deoxyuridine, 5-fluorodeoxyuridine, fluorodeoxyuridine, floxuridin, fudr, deoxyfluorouridine, fluoruridine deoxyribose, fdurd
• ChEBI: CHEBI:60761
• SMILES: OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O

Specifications

• CAS: 50-91-9
• Molecular Formula: C9H11FN2O5
• Quantity: 500 mg
• Beilstein: 2645818
• Synonym: floxuridine, 2'-deoxy-5-fluorouridine, 5-fluoro-2'-deoxyuridine, 5-fluorodeoxyuridine, fluorodeoxyuridine, floxuridin, fudr, deoxyfluorouridine, fluoruridine deoxyribose, fdurd
• InChI Key: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
• IUPAC Name: 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
• PubChem CID: 5790
• Formula Weight: 246.2
• Chemical Name or Material: 5-Fluoro-2'-deoxyuridine

• Melting Point: 148°C to 151°C
• MDL Number: MFCD00006530
• UN Number: UN2811
• Merck Index: 14,4112
• Solubility Information: Soluble in water,alcohol,isopropyl alcohol,methanol,aqueous buffers,acetone,dimethyl sulfoxide,and ethanol. Insoluble in ether,benzene and chloroform.
• SMILES: OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O
• Molecular Weight (g/mol): 246.19
• ChEBI: CHEBI:60761
• Percent Purity: ≥98%

Safety and Handling

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Serious eye damage/eye irritation Category 2
• Germ cell mutagenicity Category 2
• Skin corrosion/irritation Category 2

Hazard Statement

• H301-Toxic if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H341-Suspected of causing genetic defects.

Precautionary Statement

• P201-Obtain special instructions before use.
• P202-Do not handle until all safety precautions have been read and understood.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Floxuridine