5-Bromo-2'-deoxyuridine, 99%

Artikelnummer.	Quantity	unitSize
15443647	250 mg	250mg
11322289	1 g	1g
11332289	5 g	5g

Artikelnummer. 15443647 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. H27260.MD

Beschreibung

CAS: 59-14-3 | C9H11BrN2O5 | 307.10 g/mol

5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Spezifikation

Chemische Identifikatoren

• CAS: 59-14-3
• Molecular Formula: C9H11BrN2O5
• Molecular Weight (g/mol): 307.10
• MDL Number: MFCD00006529
• InChI Key: WOVKYSAHUYNSMH-RRKCRQDMSA-N
• Synonym: 5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine
• PubChem CID: 6035
• ChEBI: CHEBI:472552
• IUPAC Name: 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
• SMILES: OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O

• Melting Point: ∽190°C (decomposition)
• Quantity: 250 mg
• Beilstein: 30395
• Merck Index: 14,1452
• Solubility Information: Soluble in water.
• Optical Rotation: +31° (c=1 in 0.1N HCl)
• Formula Weight: 307.1
• Percent Purity: 99%
• Chemical Name or Material: 5-Bromo-2'-deoxyuridine

Sicherheit und Handhabung

Sicherheitsdatenblatt (SDS)

RUO – Research Use Only