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Thermo Scientific™ 5-Azacytidine, 99%

5-Azacytidine, CAS # 320-67-2, is an chemical analog of cytidine that acts as an inhibitor of DNA methyltransferase activity.

Brand:  Thermo Scientific™ 226620500

Code : 29

Additional Details : CAS Number : 320-67-2 Weight : 0.00100kg


Quantity 50mg

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Product Code. 10003160

  • £29.50 / 50mg
Estimated Shipment: 30-05-2022
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Description

Description

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description
5-Azacytidine is a chemical analog of the nucleoside cytidine that incorporates into DNA and inhibits DNA methylation
At low doses, 5-azacytidine irreversibly binds the enzyme DNA methyltransferase (DNMT)
Applications
5-Azacytidine has been used for cardiomyocyte differentiation from mesenchymal stem cells
It has been used as a potent DNMT inhibitor in the study of tumor cell proliferation and induction of gene expression following demethylation
5-Azacytidine can globally change histone modification patterns
Specifications

Chemical Identifiers

320-67-2
244.21
NMUSYJAQQFHJEW-KVTDHHQDSA-N
9444
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
C8H12N4O5
MFCD00006539
5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
CHEBI:2038
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N

Specifications

5-Azacytidine
320-67-2
100.0
228.0°C to 230.0°C
Authentic
MFCD00006539
15, 884
50mg
NMUSYJAQQFHJEW-KVTDHHQDSA-N
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
244.21
CHEBI:2038
Crystalline Powder
99%
98.5
White
98.5% min. (HPLC)
C8H12N4O5
Glass bottle
5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
Solubility in water: .. Other solubilities: soluble in methanol
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
+ 40.00
9444
244.21
99%
Videos
Safety and Handling

Safety and Handling

Product Identifier
  • 5-Azacytidine

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 4
  • Germ cell mutagenicity Category 1B

Hazard Statement
  • H340-May cause genetic defects.
  • H302-Harmful if swallowed.

Precautionary Statement
  • P201-Obtain special instructions before use.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

SDS Documents
Certificates
Special Offers

Special Offers

RUO – Research Use Only