5,7-Dihydroxy-4'-methoxyisoflavone, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11310528	Thermo Scientific Alfa Aesar 043853.MD	250 mg
11320528	Thermo Scientific Alfa Aesar 043853.03	1 g
11330528	Thermo Scientific Alfa Aesar 043853.06	5 g

Description

It has putative benefits in dietary cancer prophylaxis. It has also been found to inhibit fatty acid amide hydrolase and to act as agonist of PPARgamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2. It acts as an antineoplastic agent. It is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. It is a nitric oxide synthase inhibitor and apoptosis inducer

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

• CAS: 491-80-5
• Molecular Weight (g/mol): 284.27
• InChI Key: WUADCCWRTIWANL-UHFFFAOYSA-N
• PubChem CID: 5280373
• IUPAC Name: 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one

• Molecular Formula: C16H12O5
• MDL Number: MFCD00006839
• Synonym: biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
• ChEBI: CHEBI:17574
• SMILES: COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O

Specifications

• CAS: 491-80-5
• Molecular Formula: C16H12O5
• Beilstein: 278107
• Solubility Information: Soluble in water (<1mg/ml at 25°C),chloroform,methanol,DMSO (57mg/ml at 25°C),and ethanol (9mg/ml at 25°C).
• SMILES: COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
• Molecular Weight (g/mol): 284.27
• ChEBI: CHEBI:17574
• Percent Purity: 98%
• Chemical Name or Material: 5,7-Dihydroxy-4'-methoxyisoflavone

• Melting Point: 210°C to 213°C
• MDL Number: MFCD00006839
• Synonym: biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl
• InChI Key: WUADCCWRTIWANL-UHFFFAOYSA-N
• IUPAC Name: 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
• PubChem CID: 5280373
• Formula Weight: 284.27
• Physical Form: Powder

Safety and Handling

missing translation for 'einecsNumber' : 207-744-7

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only