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4'-Hydroxy-3'-methoxyacetophenone, 98%, Thermo Scientific Chemicals

Product Code. 11344719
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50 g
250 g
500 g
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4'-Hydroxy-3'-methoxyacetophenone is used as an inhibitor of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which is an enzyme responsible for reactive oxygen species production. It is also useful in the treatment of various inflammatory diseases and atherosclerosis. Further, it shows an anti-inflammatory activity and improves endothelial function by reducing oxidative stress. In addition to this, it is used for studying nitric oxide regulated processes in plants.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′-Hydroxy-3′-methoxyacetophenone is used as an inhibitor of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which is an enzyme responsible for reactive oxygen species production. It is also useful in the treatment of various inflammatory diseases and atherosclerosis. Further, it shows an anti-inflammatory activity and improves endothelial function by reducing oxidative stress. In addition to this, it is used for studying nitric oxide regulated processes in plants.

Solubility
Soluble in ethanol, chloroform, ether, hot water, benzene, ethyl acetate and dimethyl sulfoxide. Insoluble in petroleum ether.

Notes
Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 498-02-2
Molecular Formula C9H10O3
Molecular Weight (g/mol) 166.18
MDL Number MFCD00008747
InChI Key DFYRUELUNQRZTB-UHFFFAOYSA-N
Synonym acetovanillone, apocynin, 4'-hydroxy-3'-methoxyacetophenone, 1-4-hydroxy-3-methoxyphenyl ethanone, acetoguaiacone, acetoguaiacon, apocynine, 4-acetyl-2-methoxyphenol, acetovanilone, acetovanyllon
PubChem CID 2214
ChEBI CHEBI:2781
IUPAC Name 1-(4-hydroxy-3-methoxyphenyl)ethanone
SMILES COC1=CC(=CC=C1O)C(C)=O

Specifications

Melting Point 112°C to 116°C
Boiling Point 295°C to 300°C
Quantity 500 g
Beilstein 637373
Merck Index 14,741
Solubility Information Soluble in ethanol,chloroform,ether,hot water,benzene,ethyl acetate and dimethyl sulfoxide. Insoluble in petroleum ether.
Formula Weight 166.18
Percent Purity 98%
Chemical Name or Material 4'-Hydroxy-3'-methoxyacetophenone

RUO – Research Use Only

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