Thermo Scientific Chemicals 4-Epichlortetracycline hydrochloride, can be used as secondary standard

Product Code.	Quantity	Packaging	unitSize
10731331	100 mg	Glass bottle	100mg
10105160	500 mg	Glass bottle	500mg

Product Code. 10731331 Supplier Thermo Scientific Chemicals Supplier No. 268231000

Description

4-Epichlortetracycline hydrochloride, CAS # 14297-93-9, is a broad-spectrum, bacteriostatic antibiotic of the tetracycline antibiotic family.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• 4-Epichlortetracycline is the hydrochloride salt of 4-Epichlortetracycline, a tetracycline ring structure with a chloride substitution

• 4-Epichlortetracycline hydrochloride (4-Epi-chlortetracycline) is an epimer of chlortetracycline

• 4-Epichlortetracycline suppresses neutrophil activity and dampens the immune response

• Acts as an aminoacyl-tRNA analog to disrupt polypeptide synthesis, reducing bacterial growth Applications

• Can be used for in vitro research on cancer and inflammatory mechanisms

• Intended for use as a selective agent and secondary standard

Specifications

Chemical Identifiers

• CAS: 101342-45-4
• Molecular Formula: C₂₂H₂₃ClN₂O₈·ClH
• Molecular Weight (g/mol): 515.34
• MDL Number: MFCD09842537
• InChI Key: QYAPHLRPFNSDNH-PNEIEYGESA-N
• Synonym: epichlortetracycline hydrochloride
• PubChem CID: 92043146
• IUPAC Name: (4R,4aS,5aS,6R,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
• SMILES: CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)N)N(C)C)O.Cl

• CAS Min %: 96.0
• CAS Max %: 100.0
• Melting Point: 250.0°C
• Color: Orange to Yellow
• Infrared Spectrum: Authentic
• Assay Percent Range: 80% min. (as is,calculated)
• Packaging: Glass bottle
• Quantity: 100 mg
• Solubility Information: Solubility in water: 67g/L. Other solubilities: 20g/L methanol
• Formula Weight: 515.34
• Percent Purity: ≥97.0% Total Base (on anhydrous substance), ≥80 wt% (as is, calculated) (HPLC)
• Physical Form: Powder
• Chemical Name or Material: 4-Epichlortetracycline hydrochloride, 97%

Safety and Handling

Product Identifier

• 4-Epichlortetracycline hydrochloride

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Reproductive toxicity Category 2

Hazard Statement

• H319-Causes serious eye irritation.
• H361d-Suspected of damaging the unborn child.

Precautionary Statement

• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.

SDS

RUO – Research Use Only