4-Chlorobenzeneboronic acid, 98+%

Product Code. 11467577

Brand: Thermo Scientific Alfa Aesar A15657.14

Description

CAS: 1679-18-1 | C6H6BClO2 | 156.37 g/mol

Used as a GC reagent for diols. It is a reagent used for palladium-catalyzed direct arylation, cyclopalladation, tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation, copper-mediated ligandless aerobic fluoroalkylation, Pd-catalyzed arylative cyclization, ruthenium catalyzed direct arylation, ligand-free copper-catalyzed coupling reactions and regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions. Also in as a reagent in the preparation of catalysts for Suzuki-Miyaura cross-coupling, palladium(II) thiocarboxamide complexes as Suzuki coupling catalysts, Biaryls by Suzuki reactions of aryl chlorides, bromides, and iodides with arylboronic acids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used as a GC reagent for diols. It is a reagent used for palladium-catalyzed direct arylation, cyclopalladation, tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation, copper-mediated ligandless aerobic fluoroalkylation, Pd-catalyzed arylative cyclization, ruthenium catalyzed direct arylation, ligand-free copper-catalyzed coupling reactions and regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions. Also in as a reagent in the preparation of catalysts for Suzuki-Miyaura cross-coupling, palladium(II) thiocarboxamide complexes as Suzuki coupling catalysts, Biaryls by Suzuki reactions of aryl chlorides, bromides, and iodides with arylboronic acids.

Solubility
Slightly soluble in water. Soluble in DMSO.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 1679-18-1
• Molecular Formula: C6H6BClO2
• Molecular Weight (g/mol): 156.37
• MDL Number: MFCD00039137
• InChI Key: CAYQIZIAYYNFCS-UHFFFAOYSA-N
• Synonym: 4-chlorophenyl boronic acid, 4-chlorobenzeneboronic acid, p-chlorophenylboronic acid, benzeneboronic acid, p-chloro, p-chlorobenzeneboronic acid, boronic acid, 4-chlorophenyl, boronic acid, p-chlorophenyl, 4-chlorophenyl boranediol, 4-chlorophenylbornic acid
• PubChem CID: 74299
• IUPAC Name: (4-chlorophenyl)boronic acid
• SMILES: OB(O)C1=CC=C(Cl)C=C1

• Melting Point: 268°C to 277°C
• Quantity: 25 g
• Beilstein: 2936346
• Solubility Information: Slightly soluble in water. Soluble in DMSO.
• Formula Weight: 156.38
• Percent Purity: ≥98%
• Chemical Name or Material: 4-Chlorobenzeneboronic acid

Safety and Handling

Product Identifier

• 4-Chlorobenzeneboronic acid

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : (p-Chlorophenyl)metaboric acid

SDS

RUO – Research Use Only