4',5,7-Trihydroxyisoflavone, 99+%, Thermo Scientific Chemicals

Description

Inhibitor of tyrosine protein kinase

4',5,7-Trihydroxyisoflavone is used to inhibitor of tyrosine protein kinase. Genistein inhibits EGF-stimulated phosphorylation in cultured cells. Also used to explore signal transduction pathways.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,5,7-Trihydroxyisoflavone is used to inhibitor of tyrosine protein kinase. Genistein inhibits EGF-stimulated phosphorylation in cultured cells. Also used to explore signal transduction pathways.

Solubility
Soluble in chloroform, methanol. Insoluble in cold water.

Notes
Protect from heat. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 446-72-0
• Molecular Formula: C15H10O5
• Molecular Weight (g/mol): 270.24
• MDL Number: MFCD00016952
• InChI Key: TZBJGXHYKVUXJN-UHFFFAOYSA-N
• Synonym: genistein, prunetol, genisteol, 4',5,7-trihydroxyisoflavone, genisterin, sophoricol, 5,7,4'-trihydroxyisoflavone, bonistein, 5,7-dihydroxy-3-4-hydroxyphenyl-4h-chromen-4-one, genestein
• PubChem CID: 5280961
• ChEBI: CHEBI:28088
• IUPAC Name: 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
• SMILES: OC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O

• Melting Point: ∼300°C
• Color: Brown to White
• Quantity: 100 mg
• Beilstein: 263823
• Merck Index: 14,4391
• Solubility Information: Soluble in chloroform,methanol. Insoluble in cold water.
• Formula Weight: 270.24
• Percent Purity: ≥99%
• Physical Form: Powder
• Chemical Name or Material: 4',5,7-Trihydroxyisoflavone

RUO – Research Use Only