4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%

Product Code.	Quantity	unitSize
15457585	250 mg	250mg
11425830	1 g	1g

Product Code. 15457585 Supplier Thermo Scientific Alfa Aesar Supplier No. H26473.MD

Description

CAS: 30827-99-7 | C8H11ClFNO2S | 239.689 g/mol

AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.

Solubility
Soluble in water 50 mg/mL or 100% ethanol.

Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.

Specifications

Identificadores de productos químicos

• CAS: 30827-99-7
• Molecular Formula: C8H11ClFNO2S
• Molecular Weight (g/mol): 239.689
• MDL Number: MFCD00132962
• InChI Key: WRDABNWSWOHGMS-UHFFFAOYSA-N
• Synonym: 4-2-aminoethyl benzenesulfonyl fluoride hydrochloride, aebsf, aebsf hydrochloride, pefabloc sc, aebsf hcl, pefabloc, 4-2-aminoethyl benzene-1-sulfonyl fluoride hydrochloride, aebsf, hydrochloride, benzenesulfonyl fluoride, 4-2-aminoethyl-, hydrochloride, 4-2-aminoethyl benzenesulfonylfluoride hydrochloride
• PubChem CID: 186136
• IUPAC Name: 4-(2-aminoethyl)benzenesulfonyl fluoride;hydrochloride
• SMILES: C1=CC(=CC=C1CCN)S(=O)(=O)F.Cl

• Melting Point: ∼184°C (decomposition)
• Quantity: 250 mg
• UN Number: UN3261
• Beilstein: 7604627
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in water 50mg/mL or 100% ethanol.
• Formula Weight: 239.69
• Percent Purity: 97%
• Chemical Name or Material: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride

Seguridad y manipulación

Nombre del producto

• 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride

Palabra de advertencia

• Danger

Clasificación

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Indicaciones de peligro

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Consejos de prudencia

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

SDS

RUO – Research Use Only