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Invitrogen™ Human 4-1BB (CD137/TNFRSF9) ELISA Development Kit (ABTS), PeproTech®

Product Code. 17808955
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Quantity:
10 x 96 Tests
Unit Size:
Pack of 10
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Product Code. 17808955

Brand: Invitrogen™ 900K208

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Description

ELISA

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q07011
Assay Range Lot-specific
Assay Sensitivity Lot-specific
Conjugate HRP
Product Type ELISA
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 3604
Gene Symbol TNFRSF9
Kit Contents Capture Antibody, Detection Antibody, Protein Standard, HRP-conjugate
Label or Dye HRP
Quantity 10 x 96 Tests
Regulatory Status RUO
Storage Requirements Refer to product documentation for component specific storage temperature.
Target 4-1 BB (CD137)
Test Time 1 hrs 45 mins
Total Assay Time 24 hrs 30 mins
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