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Tocris Bioscience™ (-)-[3R,4S]-Chromanol 293B

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
Enantiomer that selectively inhibits the slow component of delayed rectifier K+ current (IKs). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC50 values are 1.36 and 9.6 μM respectively). Has negligible inhibitory action at KV11.1 (hERG) channels (IC50 > 30 μM).
Racemate also available.
Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 324.39 |
| Purity | >99% |
| Molecular Weight (g/mol) | 324.395 |
| Chemical Name or Material | (-)-[3R, 4S]-Chromanol 293B |
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