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  5. Tocris Bioscience™ 3PO

Tocris Bioscience™ 3PO
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Product Code. 18780128
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18780128

Brand: Tocris Bioscience™ 5121/10

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Description

PFKFB3 inhibitor

3PO is an originally reported to inhibit PFKFB3 (IC50 = 25 μM). More recent reports failed to demonstrate activity in a PFKFB3 kinase assay. Reduces glycolytic flux and suppresses glucose uptake. Inhibits endothelial cell proliferation and causes G2/M cell cycle arrest in vitro. Attenuates vessel sprouting and tumor growth in vivo. Amplifies the antiangiogenic effect of VEGFR blockade.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type 3PO
Purity >99%
Molecular Weight (g/mol) 210.23
Inhibitors 3PO

For Research Use Only

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