3-Isobutyl-1-methylxanthine

Artikelnummer.	Quantity	unitSize
15466479	100 mg	100mg

Artikelnummer. 15466479 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. J64598.MC

Beschreibung

CAS: 28822-58-4 | C10H14N4O2 | 222.25 g/mol

3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. Inhibits the growth of carcinoma cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction.

Spezifikation

• CAS: 28822-58-4
• Melting Point: 200°C to 201°C
• Molecular Formula: C10H14N4O2
• MDL Number: MFCD00005584
• Quantity: 100 mg
• Synonym: 3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine
• Solubility Information: Soluble in ethanol.
• InChI Key: APIXJSLKIYYUKG-UHFFFAOYSA-N
• SMILES: CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O
• IUPAC Name: 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
• Molecular Weight (g/mol): 222.25
• PubChem CID: 3758
• ChEBI: CHEBI:43253
• Formula Weight: 222.24
• Physical Form: Solid
• Chemical Name or Material: 3-Isobutyl-1-methylxanthine

Sicherheit und Handhabung

Produktidentifikator

• 3-Isobutyl-1-methylxanthine

Signalwort

• Warning

Gefahrenkategorie

• Acute toxicity Category 4

Gefahrenhinweis

• H302-Harmful if swallowed.

Sicherheitshinweis

• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.

Ergänzende Informationen

• MIXTURE LIST-Contain: 3,7-Dihydro-3-isobutyl-1-methyl-1H-purine2,6-dione

RUO – Research Use Only