missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 30001570

Tocris Bioscience™ 3-Deazaneplanocin A hydrochloride

Product Code. 30001570
Change view
Click to view available options
Quantity:
1 mg
Unit Size:
1mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
30001570 1 mg 1mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 30001570 Supplier Tocris Bioscience™ Supplier No. 4703/1

Please to purchase this item. Need a web account? Register with us today!

174.20 GBP valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
This item is not returnable. View return policy

Description

EZH2 histone methyltransferase inhibitor

3-Deazaneplanocin A hydrochloride is a histone methyltransferase inhibitor; decreases global histone methylation. 3-Deazaneplanocin A hydrochloride inhibits EZH2 histone methyltransferase and s-adenosylhomocysteine (SAH) hydrolase activity. Blocks trimethylation of lysine 27 on histone H3 and lysine 20 on histone H4 in vitro. 3-Deazaneplanocin A hydrochloride induces apoptosis in multiple cancer cell lines and has no apoptotic effect on normal cells. Enhances Oct4 expression in chemically induced pluripotent stem cells (CiPSCs).

DZNep synthesized to Ancillary Material Grade also available.

For more information about how 3-Deazaneplanocin A hydrochloride may be used, see our protocol: Highly Efficient Generation of CiPSCs from MEFs

TRUSTED_SUSTAINABILITY

Specifications

CAS 120964-45-6
Quantity 1 mg
Molecular Formula C12H15ClN4O3
Formula Weight 298.73
Purity >98%
Molecular Weight (g/mol) 298.727
Chemical Name or Material 3-Deazaneplanocin A hydrochloride
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.