Alfa Aesar™ 3-Bromocyclohexene, 95%, stab. with 300-1000ppm Propylene oxide


Overview
Brand: Alfa Aesar™

Manufacturer Part Number: A10370-14

3-BROMOCYCLOHEXENE 25G

UNSPSC: 12352101

Code: NEW

Additional Details:
Additional Details: CAS Number: 1521-51-3 Weight: 0.01000kg


Quantity 25g

Product Code. 11444183

Quantity Price
1 £ 102.29 / 25g
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Chemical Identifiers

Chemical Name or Material 3-Bromocyclohexene
CAS 1521-51-3
Name Note Stabilized with 300 to 1000ppm Propylene oxide
Molecular Formula C6H9Br
Formula Weight 161.05g/mol
MDL Number MFCD00013775
UN Number UN1993
Beilstein 635953
Synonym 2-Cyclohexenyl bromide

Specification

Boiling Point 64° to 65°C (15mmHg)
Quantity 25g
Flash Point 54°C (129°F)
Chemical Name or Material 3-Bromocyclohexene
Name Note Stabilized with 300 to 1000ppm Propylene oxide
CAS 1521-51-3
Assay 95%
Molecular Formula C6H9Br
Formula Weight 161.05g/mol
MDL Number MFCD00013775
UN Number UN1993
Beilstein 635953
Synonym 2-Cyclohexenyl bromide
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapor.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces.
- No smoking.
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage 2°C to 8°C
DOT Information Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.

Applications
In peptide synthesis, can be used to protect the hydroxyl group of serine and threonine as the cyclohexyl (Chx) ether, by reaction with the sodium alkoxide (generated with NaH), followed by hydrogenation. The group is stable to TFA and 20% piperidine in DMF, but can be cleaved with TfOH in TFA, in the presence of thioanisole as a cation scavenger. It is also used in the synthesis of N-tert-butoxycarbonyl-O-cyclohexyl-L-tyrosine.1 It was also used in the synthesis of enantiopure cyclohexitols such as muco-quercitol, D-chiro-inocitol and allo-inocitol.

Solubility
Not miscible or difficult to mix in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Safety and Handling

Warning

GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapor.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces.
- No smoking.
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

2°C to 8°C