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Invitrogen™ TYRO3 Monoclonal Antibody (6D6F10)
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Product Code. 11375373
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Quantity:
100 μL
Unit Size:
100µL
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11375373 100 μL 100µL
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Product Code. 11375373 Supplier Invitrogen™ Supplier No. MA515404

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Description

Mouse Monoclonal Antibody

MA5-15404 targets Tyro3 in indirect ELISA, IF applications and shows reactivity with Human samples. The MA5-15404 immunogen is purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.

TYRO3 (tyrosine-protein kinase receptor TYRO3) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. It regulates many physiological processes including cell survival, migration, and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by a ligand, TYRO3 plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation, signal transduction, cell adhesion. and cytoskeleton reorganization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TYRO3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 6D6F10
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene TYRO3
Gene Accession No. P55146, Q06418
Gene Alias AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; Dtk; Etk-2; etk2/tyro3; FLJ16467; Rek; Rse; Sky; soluble tyro 3; soluble tyro3; styro 3; styro3; TIF; TK19-2; tyro 3; TYRO3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; Tyrosine-protein kinase TIF
Gene Symbols TYRO3
Host Species Mouse
Immunogen Purified recombinant fragment of Tyro3 (aa138-321) expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25232, 7301
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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