Alfa Aesar™ 3,5-Dibromopyridine, 98+%


Overview
Brand: Alfa Aesar™

Manufacturer Part Number: A10875-22

3,5-DIBROMOPYRIDINE, 98% 100G

UNSPSC: 12352005

Code: NEW

Additional Details:
Additional Details: CAS Number: 625-92-3 Weight: 0.01000kg


Quantity 100g

Product Code. 11444223

Quantity Price
1 £ 267.12 / 100g
Estimated Shipment date
from Supplier 12-12-2016
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Description and Specification

Chemical Identifiers

Chemical Name or Material 3,5-Dibromopyridine
CAS 625-92-3
Molecular Formula C5H3Br2N
Formula Weight 236.90g/mol
MDL Number MFCD00014634
Beilstein 108477

Specification

Melting Point 110° to 113°C
Quantity 100g
Chemical Name or Material 3,5-Dibromopyridine
CAS 625-92-3
Assay ≥98%
Molecular Formula C5H3Br2N
Formula Weight 236.90g/mol
MDL Number MFCD00014634
Beilstein 108477
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H301-H311-H332-H315-H319-H335
Toxic if swallowed.
Toxic in contact with skin.
Harmful if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P301+P310-P305+P351+P338-P361-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
Remove/Take off immediately all contaminated clothing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Applications
3-Acetylamino-5-ethoxypyridine was prepared by converting 3, 5-dibromopyridine with sodium ethylate into 3-bromo-5-ethoxypyridine, allowing this substance to interact with ammonia and acetylating the aminoethoxypyridine thus formed with acetic anhydride. Lithiation of 3, 5-dibromopyridine with LDA and subsequent reaction with electrophiles provided 4-alkyl-3, 5-dibromopyridines 2 in high yield. Ligand was prepared by a Pd(0)-catalyzed cross-coupling reaction of 3,5-dibromopyridine and 5-tributylstannyl-3,3′-bipyridine. The synthesis of 3, 5-bis (2-indolyl) pyridine and 3-[(2-indolyl)-5-phenyl] pyridine derivatives as includes Stille or Suzuki type reactions, which were realized on the 3,5-dibromopyridine.

Solubility
Soluble in Chloroform and Methanol. Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, alkali metals, moisture.

Safety and Handling

Danger

GHS H Statement
H301-H311-H332-H315-H319-H335
Toxic if swallowed.
Toxic in contact with skin.
Harmful if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P301+P310-P305+P351+P338-P361-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
Remove/Take off immediately all contaminated clothing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.