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  6. 3,3',5-Triiodo-L-thyronine, 95%, Thermo Scientific Chemicals

3,3',5-Triiodo-L-thyronine, 95%, Thermo Scientific Chemicals

Catalog Number p-7032561
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Quantity:
250 mg
1 g
5 g
This item is not returnable. View return policy
6893-02-3
C15H12I3NO4
650.98
MFCD00002593
AUYYCJSJGJYCDS-UHFFFAOYNA-N
liothyronine, triiodothyronine, 3,3',5-triiodo-l-thyronine, liothyronin, tresitope, 3,5,3'-triiodothyronine, l-liothyronine, triothyrone, liothyroninum, liotironina
5920
CHEBI:18258
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O
This item is not returnable. View return policy
6893-02-3
C15H12I3NO4
650.98
MFCD00002593
AUYYCJSJGJYCDS-UHFFFAOYNA-N
liothyronine, triiodothyronine, 3,3',5-triiodo-l-thyronine, liothyronin, tresitope, 3,5,3'-triiodothyronine, l-liothyronine, triothyrone, liothyroninum, liotironina
5920
CHEBI:18258
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O

Description

Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3', 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3', 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3'-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3?,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3′, 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3′, 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3′-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3′,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.

Solubility
Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.

Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, Strong bases, light.
TRUSTED_SUSTAINABILITY
Melting Point 234°C to 238°C
Quantity 250 mg
Sensitivity Light sensitive
Solubility Information Insoluble in water,ethanol and propylene glycol. Soluble in dilute alkalies.
Optical Rotation +25° (c=1 in 1M HCl/Ethanol 1:2)
Formula Weight 650.97
Percent Purity 95%
Chemical Name or Material 3,3',5-Triiodo-L-thyronine

RUO – Research Use Only

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