2-Thiouracil, 99%, Thermo Scientific Chemicals

Description

2-Thiouracil, Thiouracil or 4-Hydroxy-2-mercaptopyrimidine, CAS # 141-90-2, is the modified analog of the nucleotide base, uracil.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• 2-Thiouracil (Thiouracil or 4-Hydroxy-2-mercaptopyrimidine) is a nucleotide analog with a C-2 thioxo substitution
• 2-Thiouracil is a melanocyte suppressor and thyroid inhibitor

Applications
• 2-Thiouracil can be used to inhibit nitric oxide synthase and suppresses nitric oxide signaling in vitro
• 2-Thiouracil can be used for labeling of RNA in vitro
• 2-Thiouracil is intended for research applications only

Specifications

Chemical Identifiers

• CAS: 141-90-2
• Molecular Formula: C4H4N2OS
• Molecular Weight (g/mol): 128.15
• MDL Number: MFCD00006039
• InChI Key: ZEMGGZBWXRYJHK-UHFFFAOYSA-N
• Synonym: 2-thiouracil, thiouracil, 4-hydroxy-2-mercaptopyrimidine, antagothyroid, antagothyroil, deracil, nobilen, 2-thioxo-2,3-dihydropyrimidin-4 1h-one, 2-mercaptopyrimidin-4-ol, 2-mercapto-4-hydroxypyrimidine
• PubChem CID: 1269845
• ChEBI: CHEBI:348530
• IUPAC Name: 2-sulfanylidene-1H-pyrimidin-4-one
• SMILES: O=C1NC(=S)NC=C1

• CAS Min %: 98.5
• CAS Max %: 100.0
• Melting Point: >300.0°C
• Color: White to Cream
• Loss on Drying: 0.5% max. (105°C, 3 hrs)
• Infrared Spectrum: Authentic
• Assay Percent Range: 98.5% min. (HPLC)
• Packaging: Plastic bottle
• Quantity: 500 g
• Beilstein: 24, 323
• Merck Index: 15, 9520
• Solubility Information: Solubility in water: 0.5g/L. Other solubilities: soluble in alkaline solutions
• Formula Weight: 128.15
• Percent Purity: 99%
• Physical Form: Fine Crystalline Powder
• Chemical Name or Material: 2-Thiouracil

RUO – Research Use Only