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Thermo Scientific™ TheraPure™ 2'-OMe-G Phosphoramidite, 20-400 finish bottle

Artikelnummer. 17967112 Alle ansehen Thermo Scientific Produkte
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Artikelnummer. 17967112 Lieferant Thermo Scientific™ Lieferanten-Nr. 27204610
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2'-OMe-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methyl-guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular formula: C45H56N7O9P
Base: G
Base Protection: iBu
Formula weight: 869.9 g/mol
CAS number: 150780-67-9
HPLC purity: ≥99%; M-11 Impurity: ≤0.01%; Single critical impurity ≤0.3%
31P NMR purity: >99%; Sum of non-primary peaks at 140-152 ppm ≤0.5%

TRUSTED_SUSTAINABILITY

Spezifikation

For Use With (Equipment) Expedite Synthesizers
Product Type 2in-OMe-G CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Guanosine (G)
Reagent Features 2in-OMe modified
Shipping Condition Room Temperature
Purity 99%
Quantity 1 g
Reagent Type Phosphoramidite
Grade TheraPure™
Nucleic Acid Type RNA
Product Line TheraPure
Form Powder
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For Research Use Only. Not for use in diagnostic procedures.

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