Thermo Scientific™ 2'-OMe-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle

Product Code. 17984162

Brand: Thermo Scientific™ 27184210

Description

2'-OMe-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• HPLC purity—≥98.0%; Sum of non-primary peaks 140-152ppm: ≤0.5%

Specifications

• 31P NMR Purity: ≥98.0%
• Format: Amber bottle (20-400 finish neck style)
• For Use With (Equipment): Expedite Synthesizers
• Description: Base: A
  Base Protection: Bz
• Molecular Weight (g/mol): 887.97 g/mol
• Product Type: 2in-OMe-Bz-A CEP
• Content And Storage: Store in freezer (at or below -20°C).
• Nucleoside Type: Adenosine (A)
• Reagent Features: 2in-OMe modified
• Shipping Condition: Room Temperature
• Purity: 98%
• Quantity: 1 g
• Reagent Type: Phosphoramidite
• Grade: Standard
• Nucleic Acid Type: RNA
• For Use With (Application): Oligonucleotide synthesis
• Form: Powder
• Chemical Name or Material: 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O-methyl-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular Formula: C₄₈H₅₄N₇O₈P
• CAS: 110782-31-5

For Research Use Only. Not for use in diagnostic procedures.