Thermo Scientific™ 2'-OMe-Ac-C Phosphoramidite, standard grade, 20-400 finish bottle

Product Code. 17964242

Brand: Thermo Scientific™ 27182310

Description

2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-Ac-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• HPLC purity—≥98.0%; Sum of PIII impurities (140-152ppm) ≤0.5%

Specifications

• 31P NMR Purity: ≥98.0%
• Format: Amber bottle (20-400 finish neck style)
• For Use With (Equipment): Expedite Synthesizers
• Description: Base: C
  Base Protection: Ac
• Molecular Weight (g/mol): 801.86 g/mol
• Product Type: 2in-OMe-Ac-C CEP
• Content And Storage: Store in freezer (at or below -20°C).
• Nucleoside Type: Cytidine (C)
• Reagent Features: 2in-OMe modified, Fast deprotection
• Shipping Condition: Room Temperature
• Purity: ≥98% (HPLC)
• Quantity: 1 g
• Reagent Type: Phosphoramidite
• Grade: Standard
• Nucleic Acid Type: RNA
• For Use With (Application): Oligonucleotide synthesis
• Form: Powder
• Chemical Name or Material: 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular Formula: C₄₂H₅₂N₅O₉P
• CAS: 199593-09-4

For Research Use Only. Not for use in diagnostic procedures.